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Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: AFGSITGPAH WEVLLRARAI ETQCYVVAAA QCGRHHEKRA SYGHSMVVDP WGTVVARCSE GPGLCLARID LNYLRQLRRH LPVFQHRRPD LYGNLGHPLS
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Deaminated glutathione amidase; dGSH amidase; MGC57670; Nitrilase homolog 1
基因别名: NIT1
UniProt ID: (Human) Q86X76
Entrez Gene ID: (Human) 4817