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产品信息
PA5-47212
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human NKp30/NCR3 Leu19-Thr138
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2610409
产品详细信息
In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) NKp80, rhNKp44 and rhNKp46 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activating natural killer receptor p30; activating NK-A1 receptor; CD337; lymphocyte antigen 117; Natural cytotoxicity triggering receptor 3; Natural killer cell p30-related protein; natural killer cell receptor; NK-p30
基因别名: 1C7; CD337; LY117; MALS; NCR3; NKp30
UniProt ID: (Human) O14931
Entrez Gene ID: (Human) 259197
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
inflammatory response
immune response
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
cell recognition
susceptibility to natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
susceptibility to T cell mediated cytotoxicity
