Invitrogen

NKp30 Polyclonal Antibody

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NKp30 Antibody (PA5-87302) in WB

Western blot analysis of NKp30 in extracts of rat liver. Samples were incubated with NKp30 polyclonal antibody (Product # PA5-87302) using a dilution of 1:1,000 followed by HRP Goat Anti-Rabbit IgG at 1:10,000 dilution. Lysates/proteins: 25 µg per Lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

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产品信息

PA5-87302

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant full length Human NKp30.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2804048

产品详细信息

Purity is > 95% by SDS-PAGE.

靶标信息

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010].

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Activating natural killer receptor p30; activating NK-A1 receptor; CD337; lymphocyte antigen 117; Natural cytotoxicity triggering receptor 3; Natural killer cell p30-related protein; natural killer cell receptor; NK receptor 1c7; NK-p30

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基因别名: 1C7; CD337; LY117; MALS; NCR3; NKp30

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UniProt ID: (Human) O14931

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Entrez Gene ID: (Human) 259197, (Rat) 294251

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功能

receptor activity receptor binding protein homodimerization activity cell adhesion molecule binding

参与通路

positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target inflammatory response immune response homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell recognition susceptibility to natural killer cell mediated cytotoxicity regulation of immune response susceptibility to T cell mediated cytotoxicity