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NKp44 Antibody (MA5-55296) in WB
Western Blot analysis of various lysates using NKp44 Recombinant Monoclonal Antibody (Product # MA5-55296) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
MA5-55296
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3F9Z5
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NCTR2.
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
Immunogen Sequence: MAWRALHPLL LLLLLFPGSQ AQSKAQVLQS VAGQTLTVRC QYPPTGSLYE KKGWCKEASA LVCIRLVTSS KPRTMAWTSR FTIWDDPDAG FFTVTMTDLR
靶标信息
CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD336; CD336 antigen; lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); Natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; natural killer cell receptor; NK cell activating receptor (NKp44); NK cell-activating receptor; NK-p44; NK-p44dJ149M18.1
基因别名: CD336; dJ149M18.1; LY95; NCR2; NK-p44; NKP44
UniProt ID: (Human) O95944
Entrez Gene ID: (Human) 9436
