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NLGN1 Antibody (H00022871-B01P) in WB
Western Blot analysis of NLGN1 expression in transfected 293T cell line (H00022871-T01) by NLGN1 MaxPab polyclonal antibody.
Lane 1: NLGN1 transfected lysate(90.53 KDa).
Lane 2: Non-transfected lysate.
Lane 1: NLGN1 transfected lysate(90.53 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00022871-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NLGN1 (NP_055747.1, 1 a.a. approximately 823 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MALPRCTWPN YVWRAVMACL VHRGLGAPLT LCMLGCLLQA GHVLSQKLDD VDPLVATNFG KIRGIKKELN NEILGPVIQF LGVPYAAPPT GERRFQPPEP PSPWSDIRNA TQFAPVCPQN IIDGRLPEVM LPVWFTNNLD VVSSYVQDQS EDCLYLNIYV PTEDDIRDSG GPKPVMVYIH GGSYMEGTGN LYDGSVLASY GNVIVITVNY RLGVLGFLST GDQAAKGNYG LLDLIQALRW TSENIGFFGG DPLRITVFGS GAGGSCVNLL TLSHYSEGNR WSNSTKGLFQ RAIAQSGTAL SSWAVSFQPA KYARMLATKV GCNVSDTVEL VECLQKKPYK ELVDQDIQPA RYHIAFGPVI DGDVIPDDPQ ILMEQGEFLN YDIMLGVNQG EGLKFVENIV DSDDGISASD FDFAVSNFVD NLYGYPEGKD VLRETIKFMY TDWADRHNPE TRRKTLLALF TDHQWVAPAV ATADLHSNFG SPTYFYAFYH HCQTDQVPAW ADAAHGDEVP YVLGIPMIGP TELFPCNFSK NDVMLSAVVM TYWTNFAKTG DPNQPVPQDT KFIHTKPNRF EEVAWTRYSQ KDQLYLHIGL KPRVKEHYRA NKVNLWLELV PHLHNLNDIS QYTSTTTKVP STDITFRPTR KNSVPVTSAF PTAKQDDPKQ QPSPFSVDQR DYSTELSVTI AVGASLLFLN ILAFAALYYK KDKRRHDVHR RCSPQRTTTN DLTHAQEEEI MSLQMKHTDL DHECESIHPH EVVLRTACPP DYTLAMRRSP DDVPLMTPNT ITMIPNTIPG IQPLHTFNTF TGGQNNTLPH PHPHPHSHST TRV
靶标信息
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC45115; Neuroligin-1; NLG 1
基因别名: KIAA1070; NL1; NLGN1
UniProt ID: (Human) Q8N2Q7
Entrez Gene ID: (Human) 22871
regulation of respiratory gaseous exchange by neurological system process
protein targeting
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
neuron cell-cell adhesion
nervous system development
synapse assembly
positive regulation of circadian sleep/wake cycle, wakefulness
synaptic vesicle targeting
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
neuronal signal transduction
neuron projection development
positive regulation of synaptic transmission, GABAergic
protein localization to synapse
establishment of protein localization
regulation of neuron differentiation
rhythmic process
cytoskeletal matrix organization at active zone
protein homooligomerization
protein heterotetramerization
positive regulation of filopodium assembly
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
positive regulation of dendritic spine development
negative regulation of dendritic spine morphogenesis
terminal button organization
synaptic vesicle clustering
postsynaptic membrane assembly
presynaptic membrane assembly
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
neurexin clustering involved in presynaptic membrane assembly
postsynaptic density protein 95 clustering
receptor localization to synapse
positive regulation of ruffle assembly
positive regulation of synaptic vesicle endocytosis
positive regulation of protein localization to synapse
positive regulation of intracellular signal transduction
positive regulation of synaptic vesicle exocytosis
regulation of N-methyl-D-aspartate selective glutamate receptor activity
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
positive regulation of synaptic vesicle clustering
