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Product Details
PA5-18849
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (RKDKRRQEPLRQPS) corresponding to the internal amino acids of NLGN3 (aa 732-746).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_10982837
Product Specific Information
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ASPGX1; AUTSX1; Gliotactin homolog; Neuroligin-3
Gene Aliases: HNL3; KIAA1480; NL3; NLGN3
UniProt ID: (Human) Q9NZ94
Entrez Gene ID: (Human) 54413
regulation of respiratory gaseous exchange by neurological system process
receptor-mediated endocytosis
neuron cell-cell adhesion
synapse assembly
learning
visual learning
adult behavior
social behavior
axon extension
oligodendrocyte differentiation
modulation of synaptic transmission
synapse organization
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
rhythmic synaptic transmission
excitatory postsynaptic potential
inhibitory postsynaptic potential
long-term synaptic potentiation
positive regulation of dendritic spine development
negative regulation of dendritic spine morphogenesis
vocalization behavior
negative regulation of excitatory postsynaptic potential
postsynaptic membrane assembly
presynaptic membrane assembly
positive regulation of inhibitory postsynaptic potential
regulation of long-term synaptic potentiation
positive regulation of protein localization to synapse
regulation of N-methyl-D-aspartate selective glutamate receptor activity
regulation of terminal button organization
positive regulation of excitatory postsynaptic potential
positive regulation of synaptic vesicle clustering
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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