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Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Panda, Bovine, Bat, Horse, Rabbit, Pig (100%).
NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; Epididymis tissue protein Li 185a; Neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMB-R
基因别名: BB1; BB182387; BB1R; NMB-R; NMBR
UniProt ID: (Human) P28336, (Pig) B2ZI34, (Mouse) O54799
Entrez Gene ID: (Human) 4829, (Pig) 100169653, (Rabbit) 100351510, (Bovine) 539776, (Horse) 100060776, (Mouse) 18101