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Sequence of this protein is as follows: MLRTESCRPR SPAGQVAAAS PLLLLLLLLA WCAGACRGAP ILPQGLQPEQ QLQLWNEIDD TCSSFLSIDS QPQASNALEE LCFMIMGMLP KPQEQDEKDN TKRFLFHYSK TQKLGKSNVV SSVVHPLLQL VPHLHERRMK RFRVDEEFQS PFASQSRGYF LFRPRNGRRS AGFI
This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Neuromedin-U; NmU 25; prepro-NMU
基因别名: NMU
UniProt ID: (Human) P48645
Entrez Gene ID: (Human) 10874