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NMUR2 Antibody (PA5-88771) in WB
Western blot analysis of NMUR2 in extracts of various cell lines. Samples were incubated with NMUR2 Polyclonal antibody (Product # PA5-88771) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-88771
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 326-415 of human NMUR2 (NP_0645523)
偶联物
形式
Liquid
浓度
0.14 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805119
产品详细信息
Immunogen sequence: IYNLLSRRFQ AAFQNVISSF HKQWHSQHDP QLPPAQRNIF LTECHFVELT EDIGPQFPCQ SSMHNSHLPA ALSSEQMSRT NYQSFHFNKT; Positive Samples: SGC-7901, Mouse uterus, Mouse small intestine, Rat uterus; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; G-protein-coupled receptor FM-4; growth hormone secretagogue receptor family, member 4; Neuromedin-U receptor 2; NMU-R2
基因别名: FM-4; FM4; NMU-R2; NMU2R; NMUR2; TGR-1; TGR1
UniProt ID: (Human) Q9GZQ4, (Rat) Q9ESQ4, (Mouse) Q8BZ39
Entrez Gene ID: (Human) 56923, (Rat) 64042, (Mouse) 216749
reduction of food intake in response to dietary excess
calcium ion transport
regulation of smooth muscle contraction
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
central nervous system development
grooming behavior
feeding behavior
calcium-mediated signaling
activation of phospholipase A2 activity by calcium-mediated signaling
inositol phosphate-mediated signaling
response to pain
arachidonic acid secretion
chloride transmembrane transport
chloride transport
chemical synaptic transmission
signal transduction
G-protein coupled receptor signaling pathway
