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Product Details
PA5-60663
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NOC2L. Recombinant protein control fragment (Product #RP-99837).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2644730
Product Specific Information
Immunogen sequence: LTVDEFLASG FDSESESESE NSPQAETREA REAARSPDKP GGSPSASRRK GRASEHKDQL SRLKDRDPEF YKFLQENDQS LLNFSDS
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 30%.
Target Information
INHAT (inhibitor of acetyltransferases) complex binds to histones and masks them from being substrate for acetyltransferase. Endogenous INHAT subunits, which include the Set/TAF-Ibeta oncoprotein, associate with chromatin in vivo and can block coactivator mediated transcription when transfected in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp564C186; FLJ35172; NOC2-like; NOC2-like nucleolar associated transcriptional repressor; NOC2-like protein; NOC2L nucleolar associated transcriptional repressor; novel INHAT (inhibitor of histone acetyltransferase) repressor; Novel INHAT repressor; nucleolar complex associated 2 homolog; Nucleolar complex protein 2 homolog; Protein NOC2 homolog; protein phosphatase 1, regulatory subunit 12
Gene Aliases: NET15; NET7; NIR; NOC2L; PPP1R112
UniProt ID: (Human) Q9Y3T9
Entrez Gene ID: (Human) 26155
negative regulation of transcription from RNA polymerase II promoter
negative regulation of B cell apoptotic process
transcription, DNA-templated
apoptotic process
chromatin assembly
nucleolus to nucleoplasm transport
cellular response to UV
negative regulation of histone acetylation
ribosomal large subunit biogenesis
regulation of signal transduction by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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