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产品信息
H00064318-M04
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
5E8
抗原
NOC3L (NP_071896, 702 a.a. approximately 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: PIVQRFAAHL IAGAPSEGSG ALKPELSRRS ATELFEAYSM AEMTFNPPVE SSNPKIKGKF LQGDSFLNED LNQLIKRYSS EVATESPLDF TKYLKTSLH
靶标信息
GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from "classical" C/EBP binding sites, recognizing instead unique "nonclassical" sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC3L, also designated factor for adipocyte differentiation 24 or Fad24, promotes adipogenesis by controlling DNA replication during the early stages of mitotic clonal expansion (MCE).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Factor for adipocyte differentiation 24; NOC3 protein homolog; NOC3-like DNA replication regulator; NOC3-like protein; NOC3L DNA replication regulator; nucleolar complex associated 3 homolog; Nucleolar complex protein 3 homolog; Nucleolar complex-associated protein 3-like protein
基因别名: AD24; C10orf117; FAD24; NOC3L
UniProt ID: (Human) Q8WTT2
Entrez Gene ID: (Human) 64318
