Invitrogen

NOTCH4 Polyclonal Antibody

NOTCH4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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NOTCH4 Antibody (PA5-115664) in IHC (P)

Immunohistochemistry analysis of NOTCH4 in mouse lung tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115664) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

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产品信息

PA5-115664

应用

建议稀释比

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免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human NOTCH4(Accession Q99466), corresponding to amino acid residues R1474-G1524.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2900299

产品详细信息

Antibody detects endogenous levels of total NOTCH4.

靶标信息

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).

仅用于科研。不用于诊断过程。未经明确授权不得转售。