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Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Hamster, Elephant (89%) Mouse, Rat, Panda, Bat, Dog, Rabbit, Horse (84%).
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EAR-1R; HZF2; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta variant 2; Nuclear receptor subfamily 1 group D member 2; nuclear receptor subfamily 1, group D, member 2; Orphan nuclear hormone receptor BD73; Rev-erb alpha-related receptor; Rev-erb-beta; Rev-erba beta; rev-erba-alpha-related receptor; Rev-erbabeta; RVR; V-erbA-related protein 1-related
基因别名: BD73; EAR-1R; NR1D2; RVR
UniProt ID: (Human) Q14995
Entrez Gene ID: (Human) 9975
分子生物学功能:
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator