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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MHAPGMKKIK LDTPEEIARW REERRKNYPT LANIERKKKL KLEKEKRGAV LTTTQYGKMK GMSRHSQMAK IRSPGKNHKW KNDNSRQRAV TGSGSHLCDL KLEGPPEANA DPLGVLINSD SESDKEEKPQ HSVIPKEVTP ALCSLMSSYG SLSGSESEPE ETPIKTEADV LAENQVLDSS APKSPSQDVK ATVRNFSEAK SENRKKSFEK TNPKRKKDYH NYQTLFEPRT HHPYLLEMLL APDIRHERNV ILQCVRYIIK KDFFGLDTNS AKSKDV
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FMR1-interacting protein NUFIP1; Nuclear FMR1-interacting protein 1; Nuclear FMRP-interacting protein 1; nuclear fragile X mental retardation protein interacting protein 1
基因别名: bA540M5.1; NUFIP; NUFIP1
UniProt ID: (Human) Q9UHK0
Entrez Gene ID: (Human) 26747