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NUP35 Antibody (PA5-23372) in IHC (P)
Immunohistochemical analysis of NUP35 in formalin-fixed, paraffin-embedded human brain tissue using. Samples were incubated in NUP35 polyclonal antibody (Product # PA5-23372) using a dilution of 5 µg/mL. Isotype control (top left) and this antibody (bottom left, right).
产品信息
PA5-23372
产品规格
种属反应
Bovine,
Dog,
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 280-326 of human NUP35
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2540895
靶标信息
Nucleoporin Nup35 or Mitotic phosphoprotein 44 is a nuclear protein known to be present on nuclear pore complex and is tightly associated with the nuclear membrane and lamina. This RNA associated protein belongs to the Nup53 family and has a MPPN (mitotic phosphoprotein N' end) domain. It has a small number of scattered phenylalanine-glycine repeats, but not the large domains seen in other nucleoporins. Though the exact function of NUP35 is yet to be revealed, it may function as a component of the nuclear pore complex (NPC) which are collectively referred to as nucleoporins (NUPs). It also may play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors, and may also play an important part in the association of MAD1, a transcriptional repressor with the NPC. NUP35 is widely expressed in most of the tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 35 kDa nucleoporin; Mitotic phosphoprotein 44; MP-44; Nuclear pore complex protein Nup53; nucleoporin 35kDa; Nucleoporin NUP35; Nucleoporin NUP53
基因别名: 2310006I24Rik; 35kDa; 5330402E05Rik; MP-44; MP44; NO44; NP44; NUP35; NUP53
UniProt ID: (Human) Q8NFH5, (Mouse) Q8R4R6
Entrez Gene ID: (Bovine) 511248, (Dog) 478830, (Human) 129401, (Mouse) 69482
biological_process
regulation of transcription, DNA-templated
mRNA export from nucleus
tRNA export from nucleus
NLS-bearing protein import into nucleus
nuclear pore organization
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
transmembrane transport
intracellular transport of virus
regulation of cellular response to heat
