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Positive test controls include: HeLa, LO2, Mouse thymus, Mouse lung, Mouse testis, Rat testis. The target is usually found in the following locations: Cytoplasmic side, Nucleoplasmic side, Nucleus, Nucleus membrane, Peripheral membrane protein, nuclear pore complex.
Immunogen sequence: LGGLFSQPTQ APTQSNQLIN TASALSAPTL LGDERDAILA KWNQLQAFWG TGKGYFNNNI PPVEFTQENP FCRFKAVGYS CMPSNKDEDG LVVLVFNKKE TEIRSQQQQL VESLHKVLGG NQTLTVNVEG TKTLPDDQTE VVIYVVERSP NGTSRRVPAT TLYAHFEQAN IKTQLQQLGV TLSMTRTELS PAQIKQLLQN PPAGVDPIIW EQAKVDNPDS EKLIPVPMVG FKELLRRLKV QDQMTKQHQT RLDIISEDIS ELQKNQTTSV AKIAQYKRKL MDLSHRTLQV LIKQEIQRKS G
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly repeat-containing nucleoporin subset.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 54 kDa nucleoporin; Nuclear pore complex protein Nup54; nucleoporin 54kD; nucleoporin 54kDa; Nucleoporin Nup54; Nucleoporin p54
基因别名: 3110079L04Rik; 54kDa; NUP54
UniProt ID: (Human) Q7Z3B4, (Rat) P70582, (Mouse) Q8BTS4
Entrez Gene ID: (Human) 53371, (Rat) 53372, (Mouse) 269113
分子生物学功能:
transporter