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产品信息
PA5-55638
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644906
产品详细信息
Immunogen sequence: ASLLSSNGCP DPDLVLKFGP VDSTLGFLPW HIRLTEIVSL PSHLNISYED FFSALRQYAA CEQRLGK
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 90%.
靶标信息
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cis-prenyltransferase subunit NgBR; dehydrodolichyl diphosphate syntase complex subunit NUS1; Dehydrodolichyl diphosphate synthase complex subunit NUS1; di-trans,poly-cis-decaprenylcistransferase; NgBR; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog; transport and golgi organization 14 homolog
基因别名: C6orf68; MGC:7199; NGBR; NUS1; TANGO14
UniProt ID: (Human) Q96E22
Entrez Gene ID: (Human) 116150
