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产品信息
PA5-41871
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human NXF3 (aa 435-484).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2605418
产品详细信息
Peptide sequence: SSFLVDMWYQ TEWMLCFSVN GVFKEVEGQS QGSVLAFTRT FIATPGSSSS
Sequence homology: Cow: 92%; Dog: 92%; Guinea Pig: 77%; Horse: 79%; Human: 100%; Pig: 92%; Rabbit: 92%; Rat: 77%
靶标信息
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nuclear RNA export factor 3; TAP-like protein 3; TAPL-3
基因别名: NXF3; TAPL3
UniProt ID: (Human) Q9H4D5
Entrez Gene ID: (Human) 56000
