Abnova

NXF3 Monoclonal Antibody (3A9)

产品信息

H00056000-M06

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

免疫组化（石蜡） (IHC (P))

3 µg/mL

免疫细胞化学 (ICC/IF)

10-100 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

3A9

抗原

NXF3 (AAH31616, 1 a.a. approximately 531 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunogen sequence: MSLPSGHTTG HTDQVVQRRA RCWDIYQRRF SSRSEPVNPG MHSSSHQQQD GDAAMHGAHM DSPVRYTPYT ISPYNRKGSF RKQDQTHVNM EREQKPPERR MEGNMPDGTL GSWFKITVPF GIKYNEKWLL NLIQNECSVP FVPVEFHYEN MHASFFVENA SIAYALKNVS GKIWDEDNEK ISIFVNPAGI PHFVHRELKS EKVEQIKLAM NQQCDVSQEA LDIQRLPFYP DMVNRDTKMA SNPRKCMAAS LDVHEENIPT VMSAGEMDKW KGIEPGEKCA DRSPVCTTFS DTSSNINSIL ELFPKLLCLD GQQSPRATLC GTEAHKRLPT CKGSFFGSEM LKNLVLQFLQ QYYLIYDSGD RQGLLSAYHD EACFSLSIPF NPEDSAPSSF CKFFKDSRNI KILKDPYLRG ELLKHTKLDI VDSLSALPKT QHDLSSFLVD MWYQTEWMLC FSVNGVFKEV EGQSQGSVLA FTRTFIATPG SSSSLCIVND KLFVRDTSHQ GTQSALFTLV PTAFSSSMPA FSQEQQKMLP S

靶标信息

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

仅用于科研。不用于诊断过程。未经明确授权不得转售。