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Nectin 1 Antibody (PA5-85668) in ICC/IF
Nectin 1 Polyclonal Antibody detects Nectin 1 protein by immunofluorescent analysis. Sample: DIV14 rat E18 primary cortical neurons were fixed in 4% paraformaldehyde at RT for 15 min. Green: Nectin 1 protein stained by Nectin 1 Polyclonal Antibody (Product # PA5-85668) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta-3 Tubulin Polyclonal Antibody [GT1338]diluted at 1:500. Blue: Fluoroshield with DAPI .
产品信息
PA5-85668
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the N-terminus region of human Nectin 1.
偶联物
形式
Liquid
浓度
1.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792807
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (90%), Rat (89%), Dog (95%), Pig (96%).
Positive Control: mouse brain, rat brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD111; ectodermal dysplasia 4 (Margarita Island type); herpes simplex virus type 1 sensitivity; Herpes virus entry mediator C; Herpesvirus entry mediator C; Herpesvirus Ig-like receptor; HIgR; nectin 1; Nectin cell adhesion molecule 1; nectin); Nectin-1; nectin-1 alpha; nectin-1 delta; poliovirus receptor-like 1; poliovirus receptor-related 1 (herpesvirus entry mediator C; poliovirus receptor-related 1 (herpesvirus entry mediator C); poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin); Poliovirus receptor-related protein 1
基因别名: AI835281; AW549174; CD111; CLPED1; ED4; HIgR; HV1S; HVEC; nectin-1; NECTIN1; OFC7; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12
UniProt ID: (Human) Q15223, (Mouse) Q9JKF6
Entrez Gene ID: (Human) 5818, (Rat) 192183, (Mouse) 58235
lens morphogenesis in camera-type eye
desmosome organization
iron ion transport
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
axon guidance
single organismal cell-cell adhesion
viral entry into host cell
camera-type eye morphogenesis
regulation of synapse assembly
retina development in camera-type eye
enamel mineralization
cell adhesion
viral process
immune response
signal transduction
cell recognition
adherens junction organization
