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产品信息
PA5-34472
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 19 amino acid peptide near the carboxy terminus of human NGN2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551824
产品详细信息
A suggested positive control is mouse small intestine tissue lysate.
PA5-34472 can be used with blocking peptide PEP-1514.
靶标信息
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: atonal homolog 4; bHLHa8; Class A basic helix-loop-helix protein 8; Helix-loop-helix protein mATH-4A; mATH4A; neurogenin 2; Neurogenin-2; neurogenin2; NGN-2; Protein atonal homolog 4
基因别名: Ath4a; ATOH4; BHLHA8; Math4A; NEUROG2; ngn-2; NGN2
UniProt ID: (Human) Q9H2A3, (Mouse) P70447
Entrez Gene ID: (Human) 63973, (Mouse) 11924, (Rat) 295475
transcription, DNA-templated
neuron differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
neuron migration
regulation of transcription, DNA-templated
multicellular organism development
nervous system development
axon guidance
central nervous system neuron development
neurogenesis
cell differentiation
forebrain development
cell fate commitment
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
cell maturation
