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Neurokinin 2 Receptor (NK2R) Antibody (ATR-002-200UL) in WB
Western blot analysis of rat hippocampus (lanes 1 and 3) and rat uterus (lanes 2 and 4): - 1,2. Anti-Neurokinin 2 Receptor (NK2R) Antibody (#ATR-002), (1:200).3,4. Anti-Neurokinin 2 Receptor (NK2R) Antibody ,preincubated with Neurokinin 2 Receptor/NK2R Blocking Peptide (#BLP-TR002).
产品信息
ATR-002-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHTKETLFMTGDMTHSE, corresponding to amino acid residues 351-367 of rat NK2receptor, Intracellular, N-terminus
偶联物
Unconjugated
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 7 transmembrane receptor; Neurokinin A receptor; NK-2 receptor; NK-2R; NK2; SK receptor; SKR; substance K receptor; Substance-K receptor; Tachykinin 2 (substance K) receptor; tachykinin NK-2 receptor; Tachykinin receptor 2
基因别名: Nk2r; Skr; Tac2r; Tacr2
UniProt ID: (Mouse) P30549, (Rat) P16610
Entrez Gene ID: (Mouse) 21337, (Rat) 25007
signal transduction
G-protein coupled receptor signaling pathway
tachykinin receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
positive regulation of acetylcholine secretion, neurotransmission
intestine smooth muscle contraction
negative regulation of luteinizing hormone secretion
operant conditioning
positive regulation of vascular permeability
positive regulation of ion transport
prolactin secretion
positive regulation of uterine smooth muscle contraction
response to electrical stimulus
