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Invitrogen

Neuroligin 1 Polyclonal Antibody

查看其他24个Neuroligin 1抗体
说明书
实验方案
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说明书
实验方案
技术支持

产品信息

PA5-75793

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues in Human NLGN1

偶联物

Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2

内含物

15mM sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2719521

产品详细信息

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

靶标信息

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: MGC45115; Neuroligin I; Neuroligin-1; NLG 1

基因别名: 6330415N05Rik; BB179718; KIAA1070; mKIAA1070; NL1; Nlg1; NLGN1

UniProt ID: (Human) Q8N2Q7, (Mouse) Q99K10, (Rat) Q62765

Entrez Gene ID: (Human) 22871, (Mouse) 192167, (Rat) 116647

功能
receptor activity PDZ domain binding neurexin family protein binding protein dimerization activity cell adhesion molecule binding carboxylic ester hydrolase activity scaffold protein binding protein binding cell adhesion molecule
参与通路
regulation of respiratory gaseous exchange by neurological system process protein targeting heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules neuron cell-cell adhesion nervous system development synapse assembly positive regulation of circadian sleep/wake cycle, wakefulness synaptic vesicle targeting calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules neuronal signal transduction neuron projection development positive regulation of synaptic transmission, GABAergic protein localization to synapse establishment of protein localization regulation of neuron differentiation rhythmic process cytoskeletal matrix organization at active zone protein homooligomerization protein heterotetramerization positive regulation of filopodium assembly positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic long-term synaptic potentiation positive regulation of dendritic spine development negative regulation of dendritic spine morphogenesis terminal button organization synaptic vesicle clustering postsynaptic membrane assembly presynaptic membrane assembly AMPA glutamate receptor clustering NMDA glutamate receptor clustering neurexin clustering involved in presynaptic membrane assembly postsynaptic density protein 95 clustering receptor localization to synapse positive regulation of ruffle assembly positive regulation of synaptic vesicle endocytosis positive regulation of protein localization to synapse positive regulation of intracellular signal transduction positive regulation of synaptic vesicle exocytosis regulation of N-methyl-D-aspartate selective glutamate receptor activity regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity positive regulation of excitatory postsynaptic potential positive regulation of synaptic vesicle clustering cell adhesion synaptic vesicle transport modulation of synaptic transmission synapse organization inhibitory postsynaptic potential metabolic process neuronal ion channel clustering
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