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Neurotrophin 4 (NT-4) Antibody (ANT-004-200UL) in IHC
Expression of Neurotrophin 4 in mouse spinal cord - Immunohistochemical staining of mouse spinal cord using Anti-Neurotrophin 4 (NT-4) Antibody (#ANT-004). The spinal ventral horn (VH) was very lightly stained. However, in the perimeterof the white matter (WM) there were NT-4 immunoreactive cells with a small soma (triangles) and some had a stained process (arrows).
产品信息
ANT-004-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LGEVPAAGGSPL(C), corresponding to amino acid residues 43-52 of mature human NT-4(residues 123-132 of the precursor NT-4), Intracellular
偶联物
形式
Lyophilized
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 5% sucrose, 1% BSA
内含物
0.025% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: neurotrophic factor 4; neurotrophic factor 5; Neurotrophin 4/5; Neurotrophin 5 (neurotrophin 4/5); neurotrophin 5 (neurotrophin 4/5); Neurotrophin-4; Neurotrophin-5; Neutrophic factor 4; Neutrophic factor 5; NT-4; NT-5; NT4/NT5
基因别名: 2900040K06Rik; AI462899; GLC10; GLC1O; NT-4; NT-4/5; NT-5; NT4; NT4/5; NT4P; NT5; Ntf-5; NTF4; NTF5
UniProt ID: (Human) P34130, (Rat) P34131, (Mouse) Q80VU4
Entrez Gene ID: (Human) 4909, (Rat) 25730, (Mouse) 78405
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
ganglion mother cell fate determination
long-term memory
sensory organ boundary specification
adult locomotory behavior
epidermis development
mechanoreceptor differentiation
negative regulation of neuron apoptotic process
regulation of neuron differentiation
neuron projection morphogenesis
innervation
taste bud development
regulation of synaptic plasticity
negative regulation of cell death
