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Nicotinic Acetylcholine Receptor alpha 9 (CHRNA9) Polyclonal Antibody
Application
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Nicotinic Acetylcholine Receptor alpha 9 (CHRNA9) Antibody (ANC-019-200UL) in IHC (F)
Expression of nAChR alpha 9 in rat DRG - Immunohistochemical staining of rat dorsal root ganglion (DRG) frozen sections using Anti-Nicotinic Acetylcholine Receptor alpha 9 (CHRNA9) Antibody (#ANC-019), (1:400), followed by goat- Anti-rabbit-AlexaFluor-488. nAChR alpha 9 staining (in green) appears in neuronal soma (arrows).DAPI is used as the counterstain (blue).
产品信息
ANC-019-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KDHKATNSKGSEWKK, corresponding to amino acid residues 436-450 of rat nAChR alpha 9, 2ndintracellular loop
偶联物
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 is a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor alpha 9 subunit (nAChR); acetylcholine receptor, neuronal nicotinic, alpha-9 subunit; cholinergic receptor; cholinergic receptor, nicotinic alpha 9; cholinergic receptor, nicotinic, alpha 9 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 9; NACHR alpha 9; NACHR alpha-9; neuronal acetylcholine receptor protein, alpha-9 subunit; Neuronal acetylcholine receptor subunit alpha-9; nicotinic acetylcholine receptor subunit alpha 9; Nicotinic acetylcholine receptor subunit alpha-9
基因别名: 2410015I05Rik; Acra9; CHRNA9; EG666827; Gm8311; HSA243342; NACHRA9
UniProt ID: (Human) Q9UGM1, (Rat) P43144
Entrez Gene ID: (Human) 55584, (Mouse) 231252, (Rat) 65024
signal transduction
positive regulation of cytosolic calcium ion concentration
synaptic transmission, cholinergic
inner ear morphogenesis
detection of mechanical stimulus involved in sensory perception of sound
calcium ion transmembrane transport
cation transport
cation transmembrane transport
sensory perception of sound
