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产品信息
MA5-25657
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI4E5
抗原
Full length human recombinant protein of NDEL1 produced in HEK293 cell
偶联物
形式
Liquid
浓度
0.57 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2724884
靶标信息
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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生物信息学
蛋白别名: DKFZp451M0318; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; Nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein Nudel
基因别名: EOPA; MITAP1; NDE1L1; NDE2; NDEL1; NUDEL
UniProt ID: (Human) Q9GZM8
Entrez Gene ID: (Human) 81565
establishment of mitotic spindle orientation
neuron migration
inner cell mass cell proliferation
proteolysis
microtubule nucleation
chromosome segregation
sister chromatid cohesion
mitotic centrosome separation
retrograde axonal transport
regulation of neuron projection development
cell migration
cerebral cortex radially oriented cell migration
central nervous system neuron axonogenesis
regulation of intracellular protein transport
positive regulation of GTPase activity
positive regulation of axon extension
vesicle transport along microtubule
positive regulation of axon regeneration
nuclear envelope disassembly
establishment of chromosome localization
centrosome localization
neurofilament cytoskeleton organization
activation of GTPase activity
neuron projection extension
regulation of microtubule motor activity
