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产品信息
PA5-61570
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644936
产品详细信息
Immunogen sequence: PHPLSKIPGG RGGGRDPSLS ALIYKDEKLT VTQDLPVNDG KPHIVHFQYE VTEVKVSSWD
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.
靶标信息
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AZ2; ODC-Az 2; Ornithine decarboxylase antizyme 2
基因别名: AZ2; OAZ2
UniProt ID: (Human) O95190
Entrez Gene ID: (Human) 4947
regulation of cellular amino acid metabolic process
polyamine metabolic process
polyamine biosynthetic process
negative regulation of catalytic activity
positive regulation of protein catabolic process
positive regulation of intracellular protein transport
negative regulation of polyamine transmembrane transport
