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Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bat, Bovine, Hamster, Elephant, Panda, Pig (100%).
The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hMOP; KIAA0403; M-OR-1; MOP; MOR-1; MOR-1C; Mu opiate receptor; Mu opioid receptor; mu opioid receptor hMOR-1a; Mu-type opioid receptor; mu-type opioid receptor 1; mu-type opioid receptor-like; Opioid mu receptor; Opioid Receptor; opioid receptor, mu 1; OTTHUMP00000017463
基因别名: I79_001179; LMOR; M-OR-1; MOP; MOR; MOR1; OPRM; OPRM1
UniProt ID: (Human) P35372, (Pig) Q95247, (Bovine) P79350
Entrez Gene ID: (Human) 4988, (Pig) 396802, (Bovine) 281958, (Dog) 484041, (Chinese hamster) 100770962
分子生物学功能:
G-protein coupled receptor
transmembrane signal receptor