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产品信息
PA5-21146
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 16 amino acid peptide of human ORMDL1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11153467
产品详细信息
A suggested positive control is SK-N-SH cell lysate.
PA5-21146 can be used with blocking peptide PEP-1260.
靶标信息
The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in -gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adoplin-1; ORM1-like 1; ORM1-like protein 1
基因别名: C730042F17Rik; HSPC202; ORMDL1
UniProt ID: (Human) Q9P0S3, (Mouse) Q921I0
Entrez Gene ID: (Human) 94101, (Rat) 100188936, (Mouse) 227102
