Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 2
OTC Antibody (MA5-58166) in IHC (P)
Immunohistochemistry analysis of OTC with paraffin-embedded Human small intestine tissue. The tissue was incubated with OTC Recombinant Monoclonal Antibody (Product # MA5-58166) using a 1:200 dilution (40x lens). Followed by Cy3-conjugated Goat anti-Rabbit IgG (H+L) Secondary Antibody (Red) using a 1:500 dilution. DAPI was used for nuclear staining (Blue). High pressure antigen retrieval performed with 0.01... View More
产品信息
MA5-58166
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6B6N2
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human OTC (NP_000522.3).
偶联物
Unconjugated
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LQAATPKGYE PDASVTKLAE QYAKENGTKL LLTNDPLEAA HGGNVLITDT WISMGQEEEK KKRLQAFQGY QVTMKTAKVA ASDWTFLHCL PRKPEEVDDE VFYSPRSLVF PEAENRKWTI MAVMVSLLTD YSPQLQKPKF
靶标信息
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Ornithine carbamoyltransferase, mitochondrial; ornithine transcarbamylase; Ornithine transcarbamylase, mitochondrial; OTCase
基因别名: OCTD; OTC
UniProt ID: (Human) P00480
Entrez Gene ID: (Human) 5009
