Invitrogen

OVOL2 Polyclonal Antibody

OVOL2 Antibody in Immunocytochemistry (ICC/IF)

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OVOL2 Antibody (PA5-41619) in ICC/IF

Immunofluorescence analysis of corneal endothelium cells using an anti-OVOL2 polyclonal antibody (Product # PA5-41619).

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产品信息

PA5-41619

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.2-1 µg/mL

查看2篇已发表文章 2篇已发表文章

免疫细胞化学 (ICC/IF)

2.5 µg/mL

产品规格

种属反应

Human

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the N-terminal of human OVOL2 (aa 2-51).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2605752

产品详细信息

Peptide sequence: PKVFLVKRRS LGVSVRSWDE LPDEKRADTY IPVGLGRLLH DPPEDCRSDG

Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%

靶标信息

DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription regulator.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis.

Cell metabolism

Zhang Z,Jiang Y,Su L,Ludwig S,Zhang X,Tang M,Li X,Anderton P,Zhan X,Choi M,Russell J,Bu CH,Lyon S,Xu D,Hildebrand S,Scott L,Quan J,Simpson R,Sun Q,Qin B,Collie T,Tadesse M,Moresco EMY,Beutler B

PA5-41619 was used in Western Blot to reveal that OVOL2 plays dual functions in thermogenesis and adipogenesis to maintain energy balance.

Tue Nov 01 00:00:00 EDT 2022

Twist1 is required for the development of UVB-induced squamous cell carcinoma.

Molecular carcinogenesis

Eguiarte-Solomon F,Blazanin N,Rho O,Carbajal S,Felsher DW,Tran PT,DiGiovanni J

PA5-41619 was used in Western Blotting to demonstrate a critical role for Twist1 early in the process of UVB skin carcinogenesis, and that Twist1 may be a novel target for the prevention of cutaneous squamous cell carcinoma.