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OXCT1 Antibody (PA5-112289) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of OXCT1 in A431 cells. Cells were fixed with 4% PFA, permeabilized with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with OXCT1 Polyclonal Antibody (Product # PA5-112289) (1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
产品信息
PA5-112289
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived Human OXCT1 fragment
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7
内含物
0.03% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2867025
靶标信息
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-oxoacid CoA transferase 1; 3-oxoacid CoA-transferase 1; 3-oxoacid-CoA transferase 1; SCOT; SCOT-s; somatic-type succinyl CoA:3-oxoacid CoA-transferase; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; succinyl CoA:3-oxoacid CoA transferase; Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-ketoacid-CoA transferase; succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial; Succinyl-CoA:3-oxoacid CoA transferase
基因别名: OXCT; OXCT1; SCOT
UniProt ID: (Human) P55809
Entrez Gene ID: (Human) 5019
brain development
heart development
response to nutrient
response to hormone
response to activity
positive regulation of insulin secretion involved in cellular response to glucose stimulus
ketone catabolic process
response to drug
response to starvation
response to ethanol
cellular ketone body metabolic process
ketone body catabolic process
adipose tissue development
