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Recommended positive controls: 293T, A431, Jurkat, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. May play a role in encephalic photoreception. Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Encephalopsin; NMO-1; opsin (encephalopsin); opsin 3 (encephalopsin, panopsin); Opsin-3; Panopsin; protein phosphatase 1, regulatory subunit 116
基因别名: ECPN; ERO; OPN3; PPP1R116
UniProt ID: (Human) Q9Y344, (Mouse) Q9WUK7
Entrez Gene ID: (Human) 23596, (Mouse) 13603
分子生物学功能:
G-protein coupled receptor