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Oxytocin Receptor Polyclonal Antibody

Oxytocin Receptor Antibody in Immunohistochemistry (Frozen) (IHC (F))

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Oxytocin Receptor Antibody (AVR-013-200UL) in IHC (F)

Expression ofOxytocynReceptor in rat midbrain. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-Oxytocin Receptor Antibody (#AVR-013), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. Oxytocyn Receptor immunoreactivity (green) appears in neuronal profiles (arrows) in the substantia nigra pars compacta (SNC). B. Pre-incubation of the Antibody with Oxytocin Receptor ... View More

Oxytocin Receptor Antibody in Western Blot (WB)

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产品信息

AVR-013-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化（冰冻） (IHC (F))

1:200

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

CSARYLKGSRPGE, corresponding to amino acid residues 346-358 of rat Oxtr, Intracellular, C-terminus

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.85 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor is made up of 389 amino acids and has a molecular weight of ~43,000 kDa. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium or the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating a variety of behaviors, including maternal behavior, bonding, social memory and recognition, sexual and aggressive behaviors, and stress and anxiety.

仅用于科研。不用于诊断过程。未经明确授权不得转售。