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产品信息
H00005026-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
P2RX5 (NP_002552.2, 1 a.a. approximately 422 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGQAGCKGLC LSLFDYKTEK YVIAKNKKVG LLYRLLQASI LAYLVVWVFL IKKGYQDVDT SLQSAVITKV KGVAFTNTSD LGQRIWDVAD YVIPAQGENV FFVVTNLIVT PNQRQNVCAE NEGIPDGACS KDSDCHAGEA VTAGNGVKTG RCLRRENLAR GTCEIFAWCP LETSSRPEEP FLKEAEDFTI FIKNHIRFPK FNFSKSNVMD VKDRSFLKSC HFGPKNHYCP IFRLGSVIRW AGSDFQDIAL EGGVIGINIE WNCDLDKAAS ECHPHYSFSR LDNKLSKSVS SGYNFRFARY YRDAAGVEFR TLMKAYGIRF DVMVNGKGAF FCDLVLIYLI KKREFYRDKK YEEVRGLEDS SQEAEDEASG LGLSEQLTSG PGLLGMPEQQ ELQEPPEAKR GSSSQKGNGS VCPQLLEPHR ST
靶标信息
Mmgt2 mediates Mg(2+) transport and may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells. Magnesium is an essential metal, but few selective transporters have been identified. The two separate gene products, Mmgt1 and Mmgt2, comprise the family that we have termed membrane Mg(2+) transporters (MMgTs), and the proteins reside in the membrane and mediate Mg(2+) transport. The transport of Mg(2+) is saturable and studies have identified that Mmgt2 fusion proteins reside in the Golgi complex and post-Golgi vesicles, including the early endosomes in COS-7 cells transfected with the respective tagged constructs. Among related pathways for Mmgt2 are transport and binding events, in particular, transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.
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生物信息学
蛋白别名: ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; MGC47755; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 5; purinergic receptor P2X, ligand-gated ion channel, 5
基因别名: LRH-1; P2RX5; P2X5; P2X5FL; P2X5R
UniProt ID: (Human) Q93086
Entrez Gene ID: (Human) 5026
transport
signal transduction
nervous system development
blood coagulation
positive regulation of calcium ion transport into cytosol
response to ATP
purinergic nucleotide receptor signaling pathway
positive regulation of calcium-mediated signaling
cation transmembrane transport
mitophagy in response to mitochondrial depolarization
