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产品信息
APR-010-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KPAY GTTGL PRAKR KSVR, corresponding to residues 227-244 of rat P2RY2, 3rd intracellular loop (i3) between TM5 and TM6 domains.
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP receptor; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; P2U1; P2Y ATP receptor 2; P2Y purinoceptor 2; P2Y2; Purinergic receptor; purinergic receptor P2Y, G-protein coupled, 2; purinoceptor P2Y2
基因别名: HP2U; P2RU1; P2RY2; P2U; P2U1; P2UR; P2Y2; P2Y2R
UniProt ID: (Human) P41231, (Mouse) P35383, (Rat) P41232
Entrez Gene ID: (Human) 5029, (Mouse) 18442, (Rat) 29597
in utero embryonic development
cellular ion homeostasis
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
aging
positive regulation of neuron projection development
positive regulation of smooth muscle cell migration
sensory perception of pain
negative regulation of ossification
positive regulation of prostaglandin secretion
positive regulation of chemokine production
G-protein coupled purinergic nucleotide receptor signaling pathway
wound healing
regulation of vasodilation
positive regulation of penile erection
positive regulation of mucus secretion
response to growth factor
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to purine-containing compound
