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P2Y4 Receptor Antibody (APR-006-200UL) in IHC
Expression of P2RY4 in rat cerebellum - Immunohistochemical staining of rat cerebellum using Anti-P2Y4 Receptor Antibody (#APR-006). A. P2RY4 (red) appears in astrocytic processes (arrows). B.In contrast, P2RY4 does not appearin Purkinje neuronal dendrites stained for calbindin D28k (green) in the same brain section. This demonstrates the restriction of P2RY4 to astrocytic fibers.
产品信息
APR-006-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)HEES ISRWA DTHQD, corresponding to residues 337-350 of rat P2RY4, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.9 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 5% sucrose, 1% BSA
内含物
0.025% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: P2P; P2Y ATP receptor 4; P2Y purinoceptor 4; P2Y4; P2Y4 receptor; P2YR4; purinergic receptor P2Y G-protein coupled 4; purinergic receptor P2Y, G-protein coupled 4; purinergic receptor P2Y, G-protein coupled, 4; pyrimidinergic receptor P2Y, G-protein coupled, 4; RP13-26D14.5; UNR; Uridine nucleotide receptor
基因别名: NRU; P2P; P2RY4; P2Y4; P2Y4R; UNR
UniProt ID: (Human) P51582, (Rat) O35811, (Mouse) Q9JJS7
Entrez Gene ID: (Human) 5030, (Rat) 63843, (Mouse) 57385
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
transepithelial chloride transport
G-protein coupled purinergic nucleotide receptor signaling pathway
cellular response to prostaglandin E stimulus
G-protein coupled receptor signaling pathway
signal transduction
