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P2Y6 Antibody (PA5-106912) in ICC/IF
Immunofluorescent analysis of P2Y6 in HepG2 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and P2Y6 polyclonal antibody (Product # PA5-106912) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-106912
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human P2RY6(Accession Q15077), corresponding to amino acid residues I257-K307.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854576
产品详细信息
Antibody detects endogenous levels of total P2RY6.
靶标信息
P2Y6 belongs to the family of G protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G-coupled nucleotide receptor; MGC15335; P2 purinoceptor; P2Y ATP receptor 6; P2Y purinoceptor 6; p2y3 and chick; p2y3 receptor; P2Y6; P2Y6 receptor; Purinoceptor p2y6; pyrimidinergic receptor P2Y, G-protein coupled, 6
基因别名: 2010204J23Rik; P2RY6; P2Y6; PP2891
UniProt ID: (Human) Q15077, (Rat) Q63371, (Mouse) Q9ERK9
Entrez Gene ID: (Human) 5031, (Rat) 117264, (Mouse) 233571
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of smooth muscle cell migration
transepithelial chloride transport
G-protein coupled purinergic nucleotide receptor signaling pathway
cellular response to prostaglandin E stimulus
cellular response to organic cyclic compound
G-protein coupled receptor signaling pathway
signal transduction
