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产品信息
PA5-21162
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide near the carboxy terminus of human AP3M1.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11154319
产品详细信息
A suggested positive control is human brain tissue lysate.
PA5-21162 can be used with blocking peptide PEP-1276.
靶标信息
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adapter-related protein complex 3 mu-1 subunit; adapter-related protein complex 3 subunit mu-1; Adaptor-related protein complex 3 subunit mu-1; adaptor-related protein complex AP-3 mu 1 subunit; adaptor-related protein complex AP-3, mu 1 subunit; AP-3 adapter complex mu3A subunit; AP-3 adaptor complex mu3A subunit; AP-3 complex subunit mu-1; ap3; clathrin adaptor complex AP3, mu-3A subunit; clathrin adaptor protein mu3A; clathrin assembly protein assembly protein complex 1 medium chain homolog 1; clathrin assembly protein assembly protein complex 3 mu-1 medium chain; clathrin coat assembly protein AP47 homolog 1; clathrin coat-associated protein AP47 homolog 1; clathrin-associated adaptor protein homolog (p47A); golgi adaptor AP-1 47 kDa protein homolog 1; HA1 47 kDa subunit homolog 1; Mu-adaptin 3A; Mu3A-adaptin
基因别名: 1200013D09Rik; AP3M1; C78982; P47a; R75378
UniProt ID: (Human) Q9Y2T2, (Mouse) Q9JKC8
Entrez Gene ID: (Human) 26985, (Rat) 171126, (Mouse) 55946
