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PARD3 Antibody (PA5-106519) in IHC (P)
Immunohistochemistry analysis of PARD3 in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PARD3 polyclonal antibody (Product # PA5-106519) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106519
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PARD3(Accession Q8TEW0), corresponding to amino acid residues V1141-Q1191.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854188
产品详细信息
Antibody detects endogenous levels of total PARD3.
靶标信息
This gene encodes a member of the kinesin 4 or subfamily of kinesin related proteins. This subfamily is also referred to as the chromokinesins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASBP; ASIP; atypical PKC isotype-specific interacting protein; Atypical PKC isotype-specific-interacting protein; atypical PKC-specific binding protein; Atypical PKC-specific-binding protein; bazooka; CTCL tumor antigen se2-5; Ephrin-interacting protein; FLJ21015; PAR-3; par-3 (partitioning defective 3) homolog; par-3 family cell polarity regulator alpha; par-3 partitioning defective 3 homolog; PAR3-alpha; PARD-3; Partitioning defective 3 homolog; partitioning-defective 3 homolog; PHIP; protein phosphatase 1, regulatory subunit 118; RP11-406D17.1; three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect)
基因别名: AA960621; AI256638; ASIP; Baz; D8Ertd580e; Par-3; PAR3; PAR3A; PAR3alpha; PARD-3; PARD3; PARD3A; Phip; PPP1R118; SE2-5L16; SE2-5LT1; SE2-5T2
UniProt ID: (Human) Q9NWL4, (Mouse) Q99NH2, (Rat) Q9Z340
Entrez Gene ID: (Human) 56288, (Mouse) 93742, (Rat) 81918
microtubule cytoskeleton organization
apical constriction
protein targeting to membrane
cell cycle
establishment or maintenance of cell polarity
negative regulation of peptidyl-threonine phosphorylation
single organismal cell-cell adhesion
myelination in peripheral nervous system
cell differentiation
positive regulation of myelination
regulation of actin filament-based process
wound healing, spreading of cells
cell division
centrosome localization
regulation of cellular localization
bicellular tight junction assembly
establishment of epithelial cell polarity
protein complex assembly
transforming growth factor beta receptor signaling pathway
protein kinase C-activating G-protein coupled receptor signaling pathway
axonogenesis
asymmetric cell division
establishment or maintenance of epithelial cell apical/basal polarity
