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产品信息
PA5-142390
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence CSQRADSIKPGDS (aa 423-435).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2933038
产品详细信息
Additional Information: This antibody is expected to recognise all three reported isoforms (NP_002575.1; NP_039236.1; NP_001128726.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.
靶标信息
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ37460; HuP1; paired box homeotic gene 7; Paired box protein Pax-7; paired domain gene 7; PAX7 transcriptional factor; PAX7A
基因别名: HUP1; PAX7; PAX7B; RMS2
UniProt ID: (Human) P23759
Entrez Gene ID: (Human) 5081
chromatin remodeling
transcription, DNA-templated
anatomical structure morphogenesis
regulation of cell fate commitment
skeletal muscle satellite cell commitment
spinal cord association neuron differentiation
dorsal/ventral neural tube patterning
positive regulation of histone methylation
negative regulation of apoptotic process
regulation of protein binding
skeletal muscle tissue regeneration
positive regulation of transcription from RNA polymerase II promoter
neuron fate commitment
embryonic skeletal system development
cartilage development
muscle tissue morphogenesis
positive regulation of myoblast proliferation
