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Antibody detects endogenous levels of total SUB1.
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: activated RNA polymerase II transcription cofactor 4; Activated RNA polymerase II transcriptional coactivator p15; p14; PC4; Positive cofactor 4; pR-ET2 encoded oncodevelopmental protein; RNA polymerase II transcriptional coactivator; Single-stranded DNA-binding protein p9; SUB1 homolog; TIS7
基因别名: AI842364; p14; P15; P9; PC4; RPO2TC1; SUB1
UniProt ID: (Human) P53999, (Rat) Q63396, (Mouse) P11031
Entrez Gene ID: (Human) 10923, (Rat) 192269, (Mouse) 20024