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产品信息
PA5-84277
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Anitgen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2791429
产品详细信息
Immunogen sequence: LSPVNSSNHG PVSTGSLTNR SPIEFPDTAD FLNKPSVILQ RSLGNAPNTP DFYQQLRNSD SNLCNSCGHQ MLKYVSTSES DGTDCCSGKS GEEENIFSKE SFKLMETQQE EETEKKDSRK LFQEGDKWLT EEAQSEQQTN IEQEVS
靶标信息
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CGI-PDE B; CGIP1; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B; Cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; phosphodiesterase 3B, cGMP-inhibited
基因别名: cGIPDE1; HcGIP1; PDE3B
UniProt ID: (Human) Q6SEI4
Entrez Gene ID: (Human) 5140
angiogenesis
cAMP catabolic process
negative regulation of cell adhesion
signal transduction
negative regulation of angiogenesis
cellular response to insulin stimulus
negative regulation of cell adhesion mediated by integrin
negative regulation of cAMP-mediated signaling
negative regulation of lipid catabolic process
