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产品信息
PA5-42383
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human PEMT (aa 152-199).
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2576770
产品详细信息
Peptide sequence: GWAIMHASPT GLLLTVLVAL TYIVALLYEE PFTAEIYRQK ASGSHKRS
Sequence homology: Cow: 93%; Dog: 86%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 82%
靶标信息
This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MGC2483; PE N-methyltransferase; PEAMT; PEMT2; Phosphatidylethanolamine N-methyltransferase; Phospholipid methyltransferase; PLMT
基因别名: PEAMT; PEMPT; PEMT; PEMT2; PHOMETH; PNMT
UniProt ID: (Human) Q9UBM1, (Rat) Q08388
Entrez Gene ID: (Human) 10400, (Rat) 25511
phosphatidyl-N-methylethanolamine N-methyltransferase activity
phosphatidylethanolamine N-methyltransferase activity
phosphatidylethanolamine binding
phosphatidyl-N-dimethylethanolamine N-methyltransferase activity
N-methyltransferase activity
S-adenosylmethionine-dependent methyltransferase activity
methyltransferase
transferase
metabolite interconversion enzyme
lipid metabolic process
glycerophospholipid metabolic process
phosphatidylcholine biosynthetic process
cell proliferation
negative regulation of cell proliferation
phospholipid biosynthetic process
methylation
response to vitamin
response to drug
response to amino acid
response to ethanol
S-adenosylhomocysteine metabolic process
S-adenosylmethionine metabolic process
positive regulation of lipoprotein metabolic process
positive regulation of protein targeting to mitochondrion
phospholipid metabolic process
response to nutrient
