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Immunogen sequence: GFAGTFLGDY FGILKEARVT VFPFNILDNP MYWGSTANYL GWAIM
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC2483; PEAMT; PEMT2; Phosphatidylethanolamine N-methyltransferase; Phospholipid methyltransferase; PLMT
基因别名: PEAMT; PEMPT; PEMT; PEMT2; PNMT
UniProt ID: (Human) Q9UBM1
Entrez Gene ID: (Human) 10400
分子生物学功能:
methyltransferase
transferase
metabolite interconversion enzyme