Invitrogen

PENK Polyclonal Antibody

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他7个PENK抗体

抗体检测数据 (4)
高级验证 (1)

PENK Antibody in Immunohistochemistry (IHC)

PENK Antibody in Immunohistochemistry (IHC)

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PENK Antibody (PA5-53021) in IHC

Immunohistochemical staining of PENK in human adrenal gland using a PENK Polyclonal Antibody (Product # PA5-53021) shows strong cytoplasmic positivity in glandular medulla cells.

PENK Antibody in Immunohistochemistry (IHC)

PENK Antibody in Immunohistochemistry (IHC)

PENK Antibody in Immunohistochemistry (IHC)

PENK Antibody in Western Blot (WB)

Product Image Gallery

PENK Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of PENK in human adrenal gland using a PENK Polyclonal Antibody (Product # PA5-53021) shows strong cytoplasmic positivity in glandular medulla cells.

PENK Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of PENK in human adrenal gland using PENK Polyclonal Antibody (Product # PA5-53021) shows high expression.

PENK Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of PENK in human kidney using PENK Polyclonal Antibody (Product # PA5-53021) shows low expression as expected.

PENK Antibody in Western Blot (WB) — Western blot analysis of PENK in control (vector only transfected HEK293T lysate) and PENK over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a PENK Polyclonal Antibody (Product # PA5-53021).

PENK Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of PENK demonstrates antibody specificity. Immunohistochemical analysis of PENK using anti-PENK Polyclonal Antibody (Product # PA5-53021), shows significant staining of PENK in human adrenal gland and shows minimal or weak staining in human kidney tissues. The relative expression levels of PENK within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-53021

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

-

免疫组化（石蜡） (IHC (P))

1:1,000-1:2,500

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PENK. Recombinant protein control fragment (Product #RP-89939).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2645384

产品详细信息

Immunogen sequence: ECSQDCATCS YRLVRPADIN FLACVMECEG KLPSLKIWET CKELLQLSKP ELPQDGTSTL RENSKPEESH LLAKRYGGFM KRYGGFMKKM DELYPMEPEE EANGSEILAK RYGGFMKKDA EE

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.

靶标信息

neuropeptide hormone; plays a role in the responses to stress and pain perception.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: enkephalin A; preproenkephalin; Proenkephalin-A

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基因别名: PE; PENK; PENK-A

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UniProt ID: (Human) P01210

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Entrez Gene ID: (Human) 5179

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opioid peptide activity neuropeptide hormone activity opioid receptor binding neuropeptide

参与通路

osteoblast differentiation behavioral fear response response to hypoxia startle response aggressive behavior signal transduction neuropeptide signaling pathway chemical synaptic transmission aging sensory perception response to radiation response to toxic substance glial cell proliferation sensory perception of pain response to estradiol response to lipopolysaccharide cellular response to oxidative stress response to nicotine locomotory exploration behavior response to morphine response to ethanol response to calcium ion general adaptation syndrome, behavioral process cellular response to vitamin D cellular response to cAMP cellular response to transforming growth factor beta stimulus response to epinephrine cellular response to virus positive regulation of behavioral fear response