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Immunogen sequence: DRKLVTGPGK RYLQVSKNRF DGDVGVFPLE FNKNSLTFSI PPKNKARLKK IKDDTGPVAK KPSSGKKGAT TQNSEICSGQ APTPDQPDTS KRSK
Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ataxin 8; Ataxin8; ATXN 8; C10 orf2; C10orf 2; FLJ21832; mitochondrial twinkle protein; PEO 1; Progressive external ophthalmoplegia 1 protein; SCA 8; T7 gp4-like protein with intramitochondrial nucleoid localization; T7 helicase-related protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; Twinkle mtDNA helicase; Twinkle protein, mitochondrial
基因别名: ATXN8; C10orf2; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL; TWNK
UniProt ID: (Human) Q96RR1
Entrez Gene ID: (Human) 56652