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PEX14 Antibody (PA5-96642) in IHC (P)
Immunohistochemistry analysis of PEX14 in paraffin-embedded human colon carcinoma. Samples were incubated with PEX14 Polyclonal antibody (Product # PA5-96642) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-96642
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 118-377 of human PEX14 (NP_0045561)
偶联物
形式
Liquid
浓度
0.41 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808444
产品详细信息
Immunogen sequence: GIAFGFHQLY KKYLLPLILG GREDRKQLER MEAGLSELSG SVAQTVTQLQ TTLASVQELL IQQQQKIQEL AHELAAAKAT TSTNWILESQ NINELKSEIN SLKGLLLNRR QFPPSPSAPK IPSWQIPVKS PSPSSPAAVN HHSSSDISPV SNESTSSSPG KEGHSPEGST VTYHLLGPQE EGEGVVDVKG QVRMEVQGEE EKREDKEDEE DEEDDDVSHV DEEDCLGVQR EDRRGGDGQI NEQVEKLRRP EGASNESERD; Positive Samples: Mouse liver; Cellular Location: Cytoplasmic side, Peripheral membrane protein, Peroxisome membrane
靶标信息
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; peroxisomal protein Pex14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein
基因别名: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p; R75137
UniProt ID: (Human) O75381, (Mouse) Q9R0A0
Entrez Gene ID: (Human) 5195, (Mouse) 56273
protein complex assembly
peroxisome organization
protein import into peroxisome matrix
protein import into peroxisome matrix, translocation
negative regulation of protein binding
microtubule anchoring
peroxisome transport along microtubule
negative regulation of sequence-specific DNA binding transcription factor activity
protein import into peroxisome matrix, substrate release
negative regulation of transcription, DNA-templated
protein homooligomerization
negative regulation of protein homotetramerization
transport
protein transport
protein import into peroxisome matrix, docking
