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产品信息
H00005213-B01P
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PFKM (NP_000280.1, 1 a.a. approximately 780 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTHEEHHAAK TLGIGKAIAV LTSGGDAQGM NAAVRAVVRV GIFTGARVFF VHEGYQGLVD GGDHIKEATW ESVSMMLQLG GTVIGSARCK DFREREGRLR AAYNLVKRGI TNLCVIGGDG SLTGADTFRS EWSDLLSDLQ KAGKITDEEA TKSSYLNIVG LVGSIDNDFC GTDMTIGTDS ALHRIMEIVD AITTTAQSHQ RTFVLEVMGR HCGYLALVTS LSCGADWVFI PECPPDDDWE EHLCRRLSET RTRGSRLNII IVAEGAIDKN GKPITSEDIK NLVVKRLGYD TRVTVLGHVQ RGGTPSAFDR ILGSRMGVEA VMALLEGTPD TPACVVSLSG NQAVRLPLME CVQVTKDVTK AMDEKKFDEA LKLRGRSFMN NWEVYKLLAH VRPPVSKSGS HTVAVMNVGA PAAGMNAAVR STVRIGLIQG NRVLVVHDGF EGLAKGQIEE AGWSYVGGWT GQGGSKLGTK RTLPKKSFEQ ISANITKFNI QGLVIIGGFE AYTGGLELME GRKQFDELCI PFVVIPATVS NNVPGSDFSV GADTALNTIC TTCDRIKQSA AGTKRRVFII ETMGGYCGYL ATMAGLAAGA DAAYIFEEPF TIRDLQANVE HLVQKMKTTV KRGLVLRNEK CNENYTTDFI FNLYSEEGKG IFDSRKNVLG HMQQGGSPTP FDRNFATKMG AKAMNWMSGK IKESYRNGRI FANTPDSGCV LGMRKRALVF QPVAELKDQT DFEHRIPKEQ WWLKLRPILK ILAKYEIDLD TSDHAHLEHI TRKRSGEAAV
靶标信息
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 6-phosphofructo-1-kinase; 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255|HAMAP-Rule:MF_03184}; ATP-PFK; ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184}; PFK-A; Phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase muscle; phosphofructokinase, polypeptide X; phosphofructokinase-A; phosphofructokinase-M; Phosphohexokinase; phosphohexokinase {ECO:0000255|HAMAP-Rule:MF_03184}; protein phosphatase 1, regulatory subunit 122
基因别名: ATP-PFK; GSD7; PFK-1; PFK-A; Pfk-M; PFK1; PFKA; PFKM; PFKX; PPP1R122
UniProt ID: (Human) P08237, (Rat) P47858
Entrez Gene ID: (Human) 5213, (Rat) 65152
6-phosphofructokinase activity
protein binding
ATP binding
protein C-terminus binding
kinase binding
identical protein binding
protein homodimerization activity
metal ion binding
fructose binding
phosphofructokinase activity
AMP binding
carbohydrate binding
fructose-6-phosphate binding
carbohydrate kinase
kinase
transferase
metabolite interconversion enzyme
glycogen catabolic process
fructose 6-phosphate metabolic process
glycolytic process
positive regulation of insulin secretion
glucose homeostasis
muscle cell cellular homeostasis
carbohydrate phosphorylation
protein oligomerization
canonical glycolysis
glycolysis from storage polysaccharide through glucose-1-phosphate
cellular glucose homeostasis
fructose 1,6-bisphosphate metabolic process
protein homotetramerization
