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产品信息
PGCF-601AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
GUCY2F (Guanylate cyclase 2F, retinal) is also named as GUC2F, RETGC2 and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. GUCY2F may play a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. By in situ hybridization, mRNA encoding GUCY2F is found only in the outer nuclear layer and inner segments of photoreceptor cells. By using synthetic peptide antiserum specific for each RetGC subtype, RetGC-2(GUCY2F) can be distinguished from RetGC-1 as a slightly smaller protein in immunoblots of bovine rod outer segments.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GC-F; guanylate cyclase 2D-like, membrane (retina-specific); Guanylate cyclase 2F; Guanylate cyclase 2F, retinal; Guanylate cyclase F; RETGC-2; Retinal guanylyl cyclase 2; Rod outer segment membrane guanylate cyclase 2; ROS-GC2
基因别名: A930002I06; CYGF; GC-F; GC2; GUC2DL; GUC2F; GUCY2F; RETGC-2; RETGC2; ROS-GC2
UniProt ID: (Human) P51841, (Mouse) Q5SDA5, (Rat) P51842
Entrez Gene ID: (Human) 2986, (Mouse) 245650, (Rat) 116556
adenylate cyclase activity
guanylate cyclase activity
protein kinase activity
receptor activity
ATP binding
GTP binding
protein homodimerization activity
protein heterodimerization activity
nucleotide binding
transferase activity, transferring phosphorus-containing groups
lyase activity
phosphorus-oxygen lyase activity
protein binding
guanylate cyclase
cGMP biosynthetic process
protein phosphorylation
receptor guanylyl cyclase signaling pathway
visual perception
regulation of rhodopsin mediated signaling pathway
intracellular signal transduction
detection of light stimulus involved in visual perception
cyclic nucleotide biosynthetic process
response to stimulus
